Unc13d Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Unc13d
unc-13 homolog D
MGI:1917700

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Unc13d^Jinx/Unc13d^Jinx C57BL/6J-Unc13d^Jinx/Mmucd	abnormal bone marrow morphology	J:119974
	abnormal cytokine secretion	J:119974
	abnormal macrophage physiology	J:105543
	abnormal NK cell physiology	J:119974
	absent lymph node germinal center	J:119974
	anemia	J:119974
	decreased cytotoxic T cell cytolysis	J:119974
	enlarged spleen	J:119974
	hemophagocytosis	J:119974
	increased CD8-positive, alpha-beta T cell number	J:119974
	increased monocyte cell number	J:119974
	increased neutrophil cell number	J:119974
	increased susceptibility to Herpesvirales infection	J:105543, J:119974
	increased susceptibility to Riboviria infection	J:105543, J:119974
	thrombocytopenia	J:119974
Unc13d^{tm1(KOMP)Vlcg}/Unc13d^{tm1(KOMP)Vlcg} involves: C57BL/6NTac	abnormal platelet dense granule physiology	J:231217
	decreased cerebral infarct size	J:231217
	decreased platelet aggregation	J:231217
	decreased susceptibility to ischemic brain injury	J:231217
	normal hematopoietic system phenotype	J:231217
	impaired blood coagulation	J:231217
	increased bleeding time	J:231217

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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