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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mpc2
mitochondrial pyruvate carrier 2
MGI:1917706
12 phenotypes from 2 alleles in 1 genetic background
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Allelic Composition
Genetic Background
Annotated Term Reference
Mpc2em1Finc/Mpc2em1Finc
involves: C57BL/6
embryonic lethality during organogenesis, complete penetrance J:211781
Mpc2em2Finc/Mpc2em2Finc
involves: C57BL/6
abnormal mitochondrial physiology J:211781
decreased circulating insulin level J:211781
decreased circulating triglyceride level J:211781
decreased insulin secretion J:211781
decreased oxygen consumption J:211781
normal homeostasis/metabolism phenotype J:211781
impaired glucose tolerance J:211781
increased circulating glucose level J:211781
increased circulating ketone body level J:211781
increased circulating lactate level J:211781
normal mortality/aging J:211781

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory