Rprd1b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rprd1b
regulation of nuclear pre-mRNA domain containing 1B
MGI:1917720

12 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rprd1b^{tm1a(EUCOMM)Hmgu}/Rprd1b⁺ C57BL/6N-Rprd1b^{tm1a(EUCOMM)Hmgu}/H	increased mean corpuscular hemoglobin concentration	J:165965
Rprd1b^tm1Tshu/Rprd1b^tm1Tshu Lgr5^{tm1(cre/ERT2)Cle}/Lgr5⁺ Tg(Vil1-cre)20Syr/0 involves: 129P2/OlaHsd * C57BL/6 * DBA/2	abnormal digestive system development	J:300857
Rprd1b^tm1Tshu/Rprd1b^tm1Tshu Tg(Vil1-cre)20Syr/0 involves: C57BL/6 * DBA/2	abnormal digestive system development	J:300857
	abnormal large intestine crypts of Lieberkuhn morphology	J:300857
	abnormal large intestine goblet cell morphology	J:300857
	abnormal small intestine goblet cell morphology	J:300857
	decreased body weight	J:300857
	decreased Paneth cell number	J:300857
	normal digestive/alimentary phenotype	J:300857
	impaired intestine regeneration	J:300857
	impaired wound healing	J:300857
	increased susceptibility to colitis induced morbidity/mortality	J:300857
	prenatal lethality, incomplete penetrance	J:300857

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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