Lrfn2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lrfn2
leucine rich repeat and fibronectin type III domain containing 2
MGI:1917780

32 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lrfn2^tm1.1Jaru/Lrfn2^tm1.1Jaru B6.129P2(Cg)-Lrfn2^tm1.1Jaru	abnormal bone marrow hematopoietic cell morphology	J:301285
	abnormal erythropoiesis	J:301285
	decreased body weight	J:301285
	decreased circulating erythropoietin level	J:301285
	decreased erythroid progenitor cell number	J:301285
	decreased granulocyte number	J:301285
	decreased hematocrit	J:301285
	decreased leukocyte cell number	J:301285
	decreased lymphocyte cell number	J:301285
	decreased mean corpuscular hemoglobin	J:301285
	increased erythrocyte cell number	J:301285
	increased hemoglobin content	J:301285
Lrfn2^tm1.1Jaru/Lrfn2^tm1.1Jaru B6J.129P2-Lrfn2^tm1.1Jaru	abnormal CNS synaptic transmission	J:241916
	abnormal dendritic spine morphology	J:241916
	abnormal excitatory postsynaptic currents	J:241916
	abnormal hippocampal pyramidal neuron dendrite morphology	J:241916
	abnormal hippocampus morphology	J:241916
	abnormal postsynaptic density morphology	J:241916
	abnormal social investigation	J:241916
	abnormal synapse morphology	J:241916
	abnormal synaptic plasticity	J:241916
	decreased miniature excitatory postsynaptic current frequency	J:241916
	decreased prepulse inhibition	J:241916
	decreased vocalization	J:241916
	enhanced contextual conditioning behavior	J:241916
	enhanced long-term potentiation	J:241916
	enhanced spatial learning	J:241916
	increased freezing behavior	J:241916
	increased startle reflex	J:241916
	increased stereotypic behavior	J:241916
	social withdrawal	J:241916
	weight loss	J:241916

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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