Lrfn2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lrfn2
leucine rich repeat and fibronectin type III domain containing 2
MGI:1917780

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Lrfn2^{Tg(CD2-Myb/en)5Kmw}/Lrfn2⁺ involves: C57BL/10 * CBA	abnormal bone marrow cell morphology/development	J:125805
	abnormal common myeloid progenitor cell morphology	J:125805
	abnormal lymph node morphology	J:125805
	decreased T cell number	J:126456
	decreased T cell proliferation	J:126456
Lrfn2^{Tg(CD2-Myb/en)5Kmw}/Lrfn2⁺ Tg(H2-K-Myc)1Brn/? involves: C57BL/10 * CBA * FVB/N	abnormal bone marrow cell morphology/development	J:125805
	abnormal common myeloid progenitor cell morphology	J:125805
	abnormal erythropoiesis	J:125805
	abnormal lymph node morphology	J:125805
	enlarged lymph nodes	J:125805
	enlarged spleen	J:125805
	extramedullary hematopoiesis	J:125805
	lymph node hemorrhage	J:125805
	lymph node necrosis	J:125805
	premature death	J:125805
	spleen hyperplasia	J:125805
Lrfn2^{Tg(CD2-Myb/en)5Kmw}/Lrfn2^{Tg(CD2-Myb/en)5Kmw} involves: C57BL/10 * CBA	abnormal thymus cortex morphology	J:126456
	abnormal thymus medulla morphology	J:126456
	decreased CD8-positive, alpha-beta T cell number	J:126456
	decreased double-negative T cell number	J:126456
	decreased T cell number	J:126456
	decreased T cell proliferation	J:126456
	small spleen	J:126456
	small thymus	J:126456

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24