Tln2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tln2
talin 2
MGI:1917799

7 phenotypes from 5 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tln2^{Gt(RRI434)Byg}/Tln2^{Gt(RRI434)Byg} involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:102137
Tln2^{Gt(S1-6D1)Sor}/Tln2^{Gt(S1-6D1)Sor} involves: C57BL/6	no abnormal phenotype detected	J:148426
Tln2^tm1.1Crit/Tln2^tm1.1Crit involves: 129P2/OlaHsd * BALB/cJ	centrally nucleated skeletal muscle fibers	J:153959
	normal muscle phenotype	J:153959
Tln2^tm1.1Crit/Tln2^tm1.1Crit involves: 129P2/OlaHsd * C57BL/6	abnormal skeletal muscle morphology	J:152372
Tln2^tm1Crit/Tln2^tm1Crit involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:152372
Tln2^tm2Crit/Tln2^tm2Crit involves: 129P2/OlaHsd * C57BL/6	normal cellular phenotype	J:190037
	centrally nucleated skeletal muscle fibers	J:190037
	decreased fibroblast proliferation	J:190037
	dystrophic muscle	J:190037

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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