Abraxas1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Abraxas1
BRCA1 A complex subunit
MGI:1917931

11 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Abraxas1^tm1.1Bwng/Abraxas1⁺ involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N	increased histiocytic sarcoma incidence	J:269823
	increased lung adenocarcinoma incidence	J:269823
	increased lymphoma incidence	J:269823
	increased tumor incidence	J:269823
	premature death	J:269823
Abraxas1^tm1.1Bwng/Abraxas1^tm1.1Bwng involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N	impaired double-strand DNA break repair	J:269823
	increased cellular sensitivity to DNA damaging agent induced cell death	J:269823
	increased cellular sensitivity to gamma-irradiation induced cell death	J:269823
	increased lymphoma incidence	J:269823
	increased micronucleus incidence	J:269823
	increased mortality induced by gamma-irradiation	J:269823
	increased tumor incidence	J:269823
	premature death	J:269823
	spontaneous chromosome breakage	J:269823

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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