Angptl6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Angptl6
angiopoietin-like 6
MGI:1917976

27 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Angptl6^tm1Yo/Angptl6^tm1Yo involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cardiovascular development	J:97552
	abnormal lipid homeostasis	J:97552
	abnormal visceral yolk sac morphology	J:97552
	abnormal vitelline vasculature morphology	J:97552
	abnormal white adipose tissue morphology	J:97552
	decreased core body temperature	J:97552
	decreased oxygen consumption	J:97552
	embryonic lethality during organogenesis, incomplete penetrance	J:97552
	hyperglycemia	J:97552
	increased circulating cholesterol level	J:97552
	increased circulating free fatty acids level	J:97552
	increased circulating insulin level	J:97552
	increased circulating leptin level	J:97552
	increased total body fat amount	J:97552
	insulin resistance	J:97552
	obese	J:97552
Tg(CAG-Angptl6)8.1Yo/0 involves: C57BL/6 * CBA	abnormal blood vessel morphology	J:97552
	abnormal circulating hormone level	J:97552
	abnormal white adipose tissue morphology	J:97552
	decreased body weight	J:97552
	decreased circulating leptin level	J:97552
	decreased susceptibility to diet-induced obesity	J:97552
	decreased total body fat amount	J:97552
	decreased white adipose tissue amount	J:97552
	increased adiponectin level	J:97552
	increased insulin sensitivity	J:97552
	increased oxygen consumption	J:97552
	weight loss	J:97552

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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