Setd2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Setd2
SET domain containing 2
MGI:1918177

25 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Setd2^{tm1b(NCOM)Mfgc}/Setd2^{tm1b(NCOM)Mfgc} C57BL/6N-Setd2^{tm1b(NCOM)Mfgc}/Tcp	decreased exploration in new environment	J:211773
	decreased prepulse inhibition	J:211773
	increased grip strength	J:211773
	prolonged QRS complex duration	J:211773
	short tibia	J:211773
Setd2^{tm1c(NCOM)Mfgc}/Setd2^{tm1c(NCOM)Mfgc} Tg(Lck-cre)#Zhu/0 involves: C57BL/6 * SJL/J	normal hematopoietic system phenotype	J:243973
	increased gamma-delta T cell number	J:243973
	normal neoplasm	J:243973
Setd2^tm1Zhch/Setd2^tm1Zhch involves: 129S1/Sv * C57BL/6	abnormal blood vessel morphology	J:157570
	abnormal head development	J:157570
	abnormal placenta labyrinth morphology	J:157570
	abnormal placental labyrinth vasculature morphology	J:157570
	abnormal visceral yolk sac mesenchyme morphology	J:157570
	abnormal visceral yolk sac morphology	J:157570
	abnormal vitelline vasculature morphology	J:157570
	blood vessel congestion	J:157570
	edema	J:157570
	embryonic growth retardation	J:157570
	embryonic lethality during organogenesis, complete penetrance	J:157570
	failure of chorioallantoic fusion	J:157570
	forebrain hypoplasia	J:157570
	incomplete embryo turning	J:157570
	open neural tube	J:157570
	pericardial effusion	J:157570
	pharyngeal arch hypoplasia	J:157570

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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