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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Kctd1
potassium channel tetramerisation domain containing 1
MGI:1918269
54 phenotypes from 4 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Kctd1em1(IMPC)J/Kctd1em1(IMPC)J
C57BL/6NJ-Kctd1em1(IMPC)J/Mmjax 		cataract J:211773
cornea vascularization J:211773
decreased bone mineral density J:211773
decreased heart weight J:211773
decreased mean corpuscular hemoglobin J:211773
decreased mean corpuscular volume J:211773
eye hemorrhage J:211773
increased blood urea nitrogen level J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating bilirubin level J:211773
increased circulating calcium level J:211773
increased circulating cholesterol level J:211773
increased circulating creatinine level J:211773
increased circulating HDL cholesterol level J:211773
increased circulating total protein level J:211773
increased circulating triglyceride level J:211773
increased leukocyte cell number J:211773
increased mean corpuscular hemoglobin concentration J:211773
increased vertical activity J:211773
persistence of hyaloid vascular system J:211773
sclerocornea J:211773
thrombocytopenia J:211773
Kctd1Mhdahst014/Kctd1+
C3HeB/FeJ-Kctd1Mhdahst014 		abnormal kidney physiology J:250423
anemia J:250423
decreased alkaline phosphatase activity J:250423
decreased circulating chloride level J:250423
decreased erythrocyte cell number J:250423
decreased food intake J:250423
decreased grip strength J:250423
decreased hematocrit J:250423
decreased hemoglobin content J:250423
decreased mean corpuscular hemoglobin J:250423
decreased mean corpuscular volume J:250423
decreased respiratory quotient J:250423
decreased urine albumin level J:250423
decreased urine osmolality J:250423
decreased urine pH J:250423
decreased urine uric acid level J:250423
increased blood urea nitrogen level J:250423
increased circulating amylase level J:250423
increased circulating calcium level J:250423
increased circulating creatinine level J:250423
increased circulating glucose level J:250423
increased circulating potassium level J:250423
increased circulating serum albumin level J:250423
increased urine calcium level J:250423
increased urine magnesium level J:250423
polyuria J:250423
tail dragging J:250423
tremors J:250423
trunk curl J:250423
Kctd1Mhdahst014/Kctd1Mhdahst014
C3HeB/FeJ-Kctd1Mhdahst014 		perinatal lethality, complete penetrance J:250423
Kctd1tm1c(EUCOMM)Wtsi/Kctd1tm1c(EUCOMM)Wtsi
Tg(Aqp2-cre)1Dek/0
involves: C57BL/6 * C57BL/6N * SJL 		normal renal/urinary system phenotype J:344153
Kctd1tm1c(EUCOMM)Wtsi/Kctd1tm1c(EUCOMM)Wtsi
Tg(KRT14-cre)1Amc/0
involves: C57BL/6N * C57BL/6NJ 		normal integument phenotype J:344153
Kctd1tm1c(EUCOMM)Wtsi/Kctd1tm1c(EUCOMM)Wtsi
Tg(NPHS2-cre)295Lbh/0
involves: C57BL/6J * C57BL/6N * SJL 		normal renal/urinary system phenotype J:344153
Kctd1tm1c(EUCOMM)Wtsi/Kctd1tm1c(EUCOMM)Wtsi
Tg(Six2-EGFP/cre)1Amc/0
involves: C57BL/6J * C57BL/6N * CD-1 		abnormal distal convoluted tubule morphology J:344153
abnormal kidney physiology J:344153
dilated distal convoluted tubule J:344153
increased blood urea nitrogen level J:344153
renal interstitial fibrosis J:344153
Kctd1tm1d(EUCOMM)Wtsi/Kctd1tm1d(EUCOMM)Wtsi
involves: C57BL/6N 		normal cardiovascular system phenotype J:344153
normal pigmentation phenotype J:344153
renal interstitial fibrosis J:344153
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory