Nemf Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nemf
nuclear export mediator factor
MGI:1918305

19 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nemf^em8Cx/Nemf^em8Cx C57BL/6J-Nemf^em8Cx/Cx	abnormal neuromuscular synapse morphology	J:296528
	axon degeneration	J:296528
	decreased body weight	J:296528
	muscular atrophy	J:296528
	neurodegeneration	J:296528
	peripheral nervous system degeneration	J:296528
	preweaning lethality, complete penetrance	J:296528
	respiratory distress	J:296528
Nemf^pdft/Nemf^pdft B6(C3)-Nemf^pdft/Cx	abnormal gait	J:296528
	abnormal neuromuscular synapse morphology	J:296528
	axon degeneration	J:296528
	decreased body size	J:296528
	decreased body weight	J:296528
	decreased grip strength	J:296528
	lethality at weaning, incomplete penetrance	J:296528
	lethality, complete penetrance	J:296528
	muscular atrophy	J:296528
	neurodegeneration	J:296528
	neuron degeneration	J:296528
	peripheral nervous system degeneration	J:296528
	slow postnatal weight gain	J:296528
Nemf^{tm1b(EUCOMM)Hmgu}/Nemf⁺ B6N(Cg)-Nemf^{tm1b(EUCOMM)Hmgu}/J	decreased circulating cholesterol level	J:211773
	decreased circulating glucose level	J:211773
	increased heart weight	J:211773
Nemf^{tm1b(EUCOMM)Hmgu}/Nemf^{tm1b(EUCOMM)Hmgu} B6N(Cg)-Nemf^{tm1b(EUCOMM)Hmgu}/J	abnormal tail morphology	J:211773
	preweaning lethality, complete penetrance	J:211773
Nemf^tvrm116/Nemf^tvrm116 C57BL/6J-Nemf^tvrm116/PjnCx	abnormal gait	J:296528
	abnormal neuromuscular synapse morphology	J:296528
	axon degeneration	J:296528
	decreased body size	J:296528
	decreased grip strength	J:296528
	muscular atrophy	J:296528
	neurodegeneration	J:296528
	neuron degeneration	J:296528
	peripheral nervous system degeneration	J:296528
	slow postnatal weight gain	J:296528

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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