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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Septin12
septin 12
MGI:1918339
26 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Septin12em1Lych/Septin12+
C57BL/6-Septin12em1Lych 		normal reproductive system phenotype J:324492
Septin12em1Lych/Septin12em1Lych
C57BL/6-Septin12em1Lych 		abnormal acrosome assembly J:324492
abnormal egg activation J:324492
abnormal sperm connecting piece morphology J:324492
abnormal sperm physiology J:324492
abnormal spermatid morphology J:324492
absent sperm head J:324492
asthenozoospermia J:324492
decreased fertilization frequency J:324492
globozoospermia J:324492
kinked sperm flagellum J:324492
male infertility J:324492
oligozoospermia J:324492
normal reproductive system phenotype J:324492
teratozoospermia J:324492
Septin12tm1.1Plk/Septin12+
chimera involves: 129/Sv * C57BL/6 		abnormal acrosome morphology J:147965
abnormal male germ cell apoptosis J:147965
abnormal seminiferous tubule epithelium morphology J:147965
abnormal sperm head morphology J:147965
abnormal sperm nucleus morphology J:147965
absent sperm flagellum J:147965
arrest of spermatogenesis J:147965
asthenozoospermia J:147965
decreased male germ cell number J:147965
decreased testis weight J:147965
detached acrosome J:147965
globozoospermia J:147965
kinked sperm flagellum J:147965
male infertility J:147965
oligozoospermia J:147965
Septin12tm3Plk/Septin12+
involves: 129 * C57BL/6 		asthenozoospermia J:223228
normal reproductive system phenotype J:223228
Septin12tm3Plk/Septin12tm3Plk
involves: 129 * C57BL/6 		abnormal sperm annulus morphology J:223228
abnormal sperm flagellum morphology J:223228
asthenozoospermia J:223228
kinked sperm flagellum J:223228
normal reproductive system phenotype J:223228
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory