Dmrtc2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dmrtc2
doublesex and mab-3 related transcription factor like family C2
MGI:1918491

17 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dmrtc2^tm1(cre)Knis/Dmrtc2^tm1(cre)Knis involves: 129P2/OlaHsd * C57BL/6J	abnormal gametogenesis	J:117721
	abnormal spermatid morphology	J:117721
	arrest of male meiosis	J:117721
	azoospermia	J:117721
	small testis	J:117721
	testis hypoplasia	J:117721
Dmrtc2^tm1.1Zark/Dmrtc2^tm1.1Zark Tg(Dhh-cre)1Mejr/0 involves: 129S1/Sv * C57BL/6	normal reproductive system phenotype	J:121537
	small testis	J:121537
Dmrtc2^tm1.2Zark/Dmrtc2^tm1.2Zark involves: 129S1/Sv * C57BL/6	abnormal male germ cell morphology	J:121537
	abnormal Sertoli cell morphology	J:121537
	abnormal spermatid morphology	J:121537
	abnormal spermatocyte morphology	J:121537
	abnormal spermatogenesis	J:121537
	abnormal spermatogonia morphology	J:121537
	abnormal testis development	J:121537
	arrest of male meiosis	J:121537
	decreased male germ cell number	J:121537
	decreased testis weight	J:121537
	increased male germ cell apoptosis	J:121537
	male infertility	J:121537
	normal reproductive system phenotype	J:121537

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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