Dmrtc2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dmrtc2
doublesex and mab-3 related transcription factor like family C2
MGI:1918491

17 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dmrtc2^tm1(cre)Knis/Dmrtc2^tm1(cre)Knis involves: 129P2/OlaHsd * C57BL/6J	abnormal gametogenesis	J:117721
	abnormal spermatid morphology	J:117721
	arrest of male meiosis	J:117721
	azoospermia	J:117721
	small testis	J:117721
	testis hypoplasia	J:117721
Dmrtc2^tm1.1Zark/Dmrtc2^tm1.1Zark Tg(Dhh-cre)1Mejr/0 involves: 129S1/Sv * C57BL/6	normal reproductive system phenotype	J:121537
	small testis	J:121537
Dmrtc2^tm1.2Zark/Dmrtc2^tm1.2Zark involves: 129S1/Sv * C57BL/6	abnormal male germ cell morphology	J:121537
	abnormal Sertoli cell morphology	J:121537
	abnormal spermatid morphology	J:121537
	abnormal spermatocyte morphology	J:121537
	abnormal spermatogenesis	J:121537
	abnormal spermatogonia morphology	J:121537
	abnormal testis development	J:121537
	arrest of male meiosis	J:121537
	decreased male germ cell number	J:121537
	decreased testis weight	J:121537
	increased male germ cell apoptosis	J:121537
	male infertility	J:121537
	normal reproductive system phenotype	J:121537

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24