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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pex1
peroxisomal biogenesis factor 1
MGI:1918632
41 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pex1tm1.1Hrw/Pex1tm1.1Hrw
involves: C57BL/6NTac 		abnormal bile salt homeostasis J:278655
abnormal fatty acids level J:278655
abnormal liver morphology J:278655
abnormal mitochondrial crista morphology J:278655
abnormal mitochondrial physiology J:278655
abnormal peroxisome morphology J:278655
abnormal phospholipid level J:278655
abnormal venous thrombosis J:278655
bile duct proliferation J:278655
cholestasis J:278655
decreased body size J:278655
decreased liver glycogen level J:278655
decreased survivor rate J:278655
dilated mitochondrion J:278655
enlarged liver J:278655
hepatic necrosis J:278655
hydronephrosis J:278655
hyperglycemia J:278655
increased liver adenoma incidence J:278655
increased liver cholesterol level J:278655
increased liver triglyceride level J:278655
lethality during fetal growth through weaning, incomplete penetrance J:278655
liver fibrosis J:278655
liver inflammation J:278655
phlebitis J:278655
postnatal growth retardation J:278655
postnatal lethality, incomplete penetrance J:278655
normal reproductive system phenotype J:278655
weakness J:278655
Pex1tm1.1Sjms/Pex1tm1.1Sjms
involves: 129 * C57BL/6N 		abnormal bile salt homeostasis J:210296
abnormal circulating phospholipid level J:210296
abnormal cone electrophysiology J:210296
abnormal intestinal lipid absorption J:210296
abnormal retina rod cell outer segment morphology J:210296
abnormal rod electrophysiology J:210296
bile duct proliferation J:210296
cholestasis J:210296
decreased body weight J:210296
decreased fatty acids level J:210296
increased fatty acids level J:210296
increased saturated fatty acids level J:210296
microvesicular hepatic steatosis J:210296
postnatal growth retardation J:210296
premature death J:210296
retina cone cell degeneration J:210296
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory