About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pex1
peroxisomal biogenesis factor 1
MGI:1918632
41 phenotypes from 2 alleles in 2 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Pex1tm1.1Hrw/Pex1tm1.1Hrw
involves: C57BL/6NTac 		abnormal bile salt homeostasis J:278655
abnormal fatty acids level J:278655
abnormal liver morphology J:278655
abnormal mitochondrial crista morphology J:278655
abnormal mitochondrial physiology J:278655
abnormal peroxisome morphology J:278655
abnormal phospholipid level J:278655
abnormal venous thrombosis J:278655
bile duct proliferation J:278655
cholestasis J:278655
decreased body size J:278655
decreased liver glycogen level J:278655
decreased survivor rate J:278655
dilated mitochondrion J:278655
enlarged liver J:278655
hepatic necrosis J:278655
hydronephrosis J:278655
hyperglycemia J:278655
increased liver adenoma incidence J:278655
increased liver cholesterol level J:278655
increased liver triglyceride level J:278655
lethality during fetal growth through weaning, incomplete penetrance J:278655
liver fibrosis J:278655
liver inflammation J:278655
phlebitis J:278655
postnatal growth retardation J:278655
postnatal lethality, incomplete penetrance J:278655
normal reproductive system phenotype J:278655
weakness J:278655
Pex1tm1.1Sjms/Pex1tm1.1Sjms
involves: 129 * C57BL/6N 		abnormal bile salt homeostasis J:210296
abnormal circulating phospholipid level J:210296
abnormal cone electrophysiology J:210296
abnormal intestinal lipid absorption J:210296
abnormal retina rod cell outer segment morphology J:210296
abnormal rod electrophysiology J:210296
bile duct proliferation J:210296
cholestasis J:210296
decreased body weight J:210296
decreased fatty acids level J:210296
increased fatty acids level J:210296
increased saturated fatty acids level J:210296
microvesicular hepatic steatosis J:210296
postnatal growth retardation J:210296
premature death J:210296
retina cone cell degeneration J:210296
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/03/2024
MGI 6.24 		The Jackson Laboratory