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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Epg5
ectopic P-granules 5 autophagy tethering factor
MGI:1918673
68 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Epg5em1(IMPC)H/Epg5em1(IMPC)H
C57BL/6NTac-Epg5em1(IMPC)H/H 		abnormal gait J:211773
decreased circulating glucose level J:211773
decreased circulating serum albumin level J:211773
decreased lymphocyte cell number J:211773
decreased prepulse inhibition J:211773
decreased startle reflex J:211773
hyperactivity J:211773
increased basophil cell number J:211773
increased bone mineral density J:211773
increased circulating alanine transaminase level J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating amylase level J:211773
increased circulating aspartate transaminase level J:211773
increased circulating iron level J:211773
increased large unstained cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
increased red blood cell distribution width J:211773
increased spleen weight J:211773
short tibia J:211773
tremors J:211773
Epg5M1Btlr/Epg5M1Btlr
C57BL/6J-Epg5M1Btlr 		circling J:272115
tremors J:272115
Epg5tm1Ygz/Epg5tm1Ygz
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N 		abnormal autophagy J:196603
abnormal electroretinogram waveform feature J:279837
abnormal hippocampus morphology J:196603
abnormal hippocampus pyramidal cell layer J:196603
abnormal innervation J:196603
abnormal motor capabilities/coordination/movement J:196603
abnormal motor neuron morphology J:196603
abnormal muscle fiber morphology J:196603
abnormal photoreceptor inner segment morphology J:279837
abnormal photoreceptor outer segment size J:279837
abnormal Z line morphology J:196603
astrocytosis J:279837
axonal spheroids J:196603
centrally nucleated skeletal muscle fibers J:196603
decreased b-wave amplitude J:279837
decreased body weight J:196603
decreased cerebral cortex pyramidal cell number J:196603
decreased hippocampus pyramidal cell number J:196603
decreased motor neuron number J:196603
decreased retina cone cell number J:279837
decreased skeletal muscle fiber size J:196603
decreased white adipose tissue amount J:196603
decreased white fat cell lipid droplet size J:196603
decreased white fat cell size J:196603
hindlimb paralysis J:196603
impaired autophagy J:279837
impaired coordination J:196603
increased mitochondrial size J:196603
increased retina apoptosis J:279837
kyphosis J:196603
limb grasping J:196603
normal liver/biliary system phenotype J:196603
microgliosis J:196603
muscular atrophy J:196603
neuronal cytoplasmic inclusions J:196603
poor grooming J:196603
postnatal growth retardation J:196603
premature death J:196603, J:279837
retina outer nuclear layer degeneration J:279837
retina photoreceptor degeneration J:279837
retina rod cell degeneration J:279837
rough coat J:196603
skeletal muscle fiber degeneration J:196603
thin retina outer nuclear layer J:279837
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory