Bbs7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bbs7
Bardet-Biedl syndrome 7
MGI:1918742

34 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bbs7^{tm1b(EUCOMM)Wtsi}/Bbs7⁺ B6N(Cg)-Bbs7^{tm1b(EUCOMM)Wtsi}/J	abnormal lens morphology	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating sodium level	J:211773
Bbs7^{tm1b(EUCOMM)Wtsi}/Bbs7^{tm1b(EUCOMM)Wtsi} B6N(Cg)-Bbs7^{tm1b(EUCOMM)Wtsi}/J	preweaning lethality, incomplete penetrance	J:211773
Bbs7^tm1Vcs/Bbs7^tm1Vcs involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal brain ependyma motile cilium morphology	J:226740
	abnormal cilium morphology	J:226740
	abnormal outer dense fiber morphology	J:226740
	abnormal sperm axoneme morphology	J:226740
	abnormal sperm flagellum morphology	J:226740
	abnormal sperm principal piece morphology	J:226740
	absent sperm flagellum	J:226740
	normal cellular phenotype	J:226740
	decreased birth body size	J:226740
	decreased body weight	J:226740
	decreased brain ependyma motile cilium length	J:226740
	decreased brain ependyma motile cilium number	J:226740
	decreased striatum size	J:226740
	enlarged lateral ventricles	J:226740
	enlarged third ventricle	J:226740
	increased body weight	J:226740
	increased food intake	J:226740
	normal limbs/digits/tail phenotype	J:226740
	male infertility	J:226740
	normal nervous system phenotype	J:226740
	obese	J:226740
	photoreceptor inner segment degeneration	J:226740
	photoreceptor outer segment degeneration	J:226740
	preweaning lethality, incomplete penetrance	J:226740
	normal renal/urinary system phenotype	J:226740
	retina degeneration	J:226740
	retina outer nuclear layer degeneration	J:226740
	small hippocampus	J:226740
	normal taste/olfaction phenotype	J:226740
	thin cerebral cortex	J:226740
Bbs7^tm1Vcs/Bbs7^tm1Vcs Not Specified	normal limbs/digits/tail phenotype	J:181886
	normal nervous system phenotype	J:181886
	normal vision/eye phenotype	J:181886

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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