Gas2l3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gas2l3
growth arrest-specific 2 like 3
MGI:1918780

19 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gas2l3^{tm1c(EUCOMM)Hmgu}/Gas2l3^{tm1c(EUCOMM)Hmgu} Gt(ROSA)26Sor^{tm2(cre/ERT2)Brn}/Gt(ROSA)26Sor⁺ involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N	abnormal fetal cardiomyocyte morphology	J:244087
	abnormal fetal cardiomyocyte proliferation	J:244087
	abnormal mitotic cytokinesis	J:244087
	normal cardiovascular system phenotype	J:244087
Gas2l3^{tm1c(EUCOMM)Hmgu}/Gas2l3^{tm1c(EUCOMM)Hmgu} Nkx2-5^tm2(cre)Rph/Nkx2-5⁺ involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6N	cardiac interstitial fibrosis	J:244087
	dilated cardiomyopathy	J:244087
	dilated heart	J:244087
	increased heart weight	J:244087
Gas2l3^{tm1d(EUCOMM)Hmgu}/Gas2l3^{tm1d(EUCOMM)Hmgu} involves: 129S4/SvJaeSor * C57BL/6J * C57BL/6N	abnormal cardiac thrombosis	J:244087
	abnormal fetal cardiomyocyte morphology	J:244087
	abnormal fetal cardiomyocyte proliferation	J:244087
	abnormal myocardial fiber morphology	J:244087
	cardiac interstitial fibrosis	J:244087
	decreased cardiac muscle contractility	J:244087
	decreased fetal cardiomyocyte number	J:244087
	decreased myocardial fiber number	J:244087
	dilated cardiomyopathy	J:244087
	dilated heart ventricle	J:244087
	increased fetal cardiomyocyte size	J:244087
	increased heart weight	J:244087
	increased myocardial fiber size	J:244087
	normal liver/biliary system phenotype	J:244087
	postnatal lethality, incomplete penetrance	J:244087
	premature death	J:244087

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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