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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mcm9
minichromosome maintenance 9 homologous recombination repair factor
MGI:1918817
30 phenotypes from 3 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mcm9Gt(AW0655)Wtsi/Mcm9Gt(AW0655)Wtsi
involves: 129P2/OlaHsd * C3HeB/FeJ 		abnormal seminiferous tubule morphology J:177420
abnormal spermatogonia morphology J:177420
arrest of male meiosis J:177420
decreased male germ cell number J:177420
female infertility J:177420
increased adenoma incidence J:177420
increased hepatocellular carcinoma incidence J:177420
increased ovary tumor incidence J:177420
increased tumor incidence J:177420
normal mortality/aging J:177420
oligozoospermia J:177420
ovary hyperplasia J:177420
premature ovarian failure J:177420
small testis J:177420
Mcm9Gt(AW0655)Wtsi/Mcm9Gt(XG743)Byg
involves: 129P2/OlaHsd * C3HeB/FeJ 		abnormal seminiferous tubule morphology J:177420
abnormal spermatogonia morphology J:177420
arrest of male meiosis J:177420
decreased male germ cell number J:177420
increased hepatocellular carcinoma incidence J:177420
increased ovary tumor incidence J:177420
increased tumor incidence J:177420
normal mortality/aging J:177420
oligozoospermia J:177420
small testis J:177420
Mcm9Gt(XG743)Byg/Mcm9Gt(XG743)Byg
involves: 129P2/OlaHsd * C3HeB/FeJ 		abnormal cell cycle J:177420
abnormal definitive hematopoiesis J:177420
abnormal female germ cell morphology J:177420
abnormal ovarian follicle number J:177420
abnormal seminiferous tubule morphology J:177420
abnormal spermatogonia morphology J:177420
arrest of male meiosis J:177420
decreased male germ cell number J:177420
decreased oocyte number J:177420
decreased primordial germ cell number J:177420
decreased primordial ovarian follicle number J:177420
early cellular replicative senescence J:177420
increased hepatocellular carcinoma incidence J:177420
increased ovary tumor incidence J:177420
increased tumor incidence J:177420
normal mortality/aging J:177420
oligozoospermia J:177420
normal reproductive system phenotype J:177420
small testis J:177420
spontaneous chromosome breakage J:177420
Mcm9tm1.1Geno/Mcm9tm1.1Geno
involves: 129S2/SvPas * C57BL/6J 		abnormal cell nucleus morphology J:187623
abnormal DNA replication J:187623
abnormal male germ cell apoptosis J:187623
abnormal seminiferous tubule morphology J:187623
decreased fibroblast proliferation J:187623
female infertility J:187623
increased cellular sensitivity to gamma-irradiation J:187623
oligozoospermia J:187623
polyploidy J:187623
normal reproductive system phenotype J:187623
spontaneous chromosome breakage J:187623
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory