Ms4a7 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ms4a7
membrane-spanning 4-domains, subfamily A, member 7
MGI:1918846

11 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ms4a7^em1.1Jddl/Ms4a7^em1.1Jddl B6.Cg-Ms4a7^em1.1Jddl	abnormal hematopoietic stem cell morphology	J:347975
	abnormal liver morphology	J:347975
	abnormal macrophage physiology	J:347975
	decreased circulating alanine transaminase level	J:347975
	decreased circulating aspartate transaminase level	J:347975
	decreased circulating tumor necrosis factor level	J:347975
	decreased cytokine level	J:347975
	decreased hepatocyte apoptosis	J:347975
	decreased interleukin-1 beta secretion	J:347975
	decreased macrophage cell number	J:347975
	decreased susceptibility to diet-induced hepatic steatosis	J:347975
Ms4a7^em1Jddl/Ms4a7^em1Jddl Lyz2^tm1(cre)Ifo/Lyz2⁺ B6.Cg-Lyz2^tm1(cre)Ifo Ms4a7^em1Jddl	abnormal liver morphology	J:347975
	decreased circulating alanine transaminase level	J:347975
	decreased circulating aspartate transaminase level	J:347975
	decreased circulating tumor necrosis factor level	J:347975
	decreased cytokine level	J:347975
	decreased susceptibility to diet-induced hepatic steatosis	J:347975

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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