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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cic
capicua transcriptional repressor
MGI:1918972
24 phenotypes from 4 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
CicGt(XE565)Byg/Cic+
B6.129P2-CicGt(XE565)Byg 		normal behavior/neurological phenotype J:177841
normal mortality/aging J:177841
CicGt(XE565)Byg/CicGt(XE565)Byg
involves: 129P2/OlaHsd * C57BL/6J 		abnormal pulmonary alveolus morphology J:178303
decreased body size J:178303
postnatal lethality, incomplete penetrance J:178303
Cictm1.1Jip/Cictm1.1Jip
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * SJL 		abnormal cerebellar layer morphology J:294338
abnormal dentate gyrus morphology J:294338
decreased brain weight J:294338
postnatal growth retardation J:294338
preweaning lethality, complete penetrance J:294338
thin cerebral cortex J:294338
Cictm1b(KOMP)Wtsi/Cic+
involves: C57BL/6N 		hyperactivity J:240674
Cictm1c(KOMP)Wtsi/Cictm1c(KOMP)Wtsi
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6 * C57BL/6N 		abnormal cerebral cortex morphology J:240674
abnormal pyramidal neuron dendrite morphology J:240674
decreased anxiety-related response J:240674
decreased cerebral cortex cell number J:240674
decreased dentate gyrus size J:240674
decreased neurotransmitter release J:240674
impaired contextual conditioning behavior J:240674
increased locomotor activity J:240674
thin cerebral cortex J:240674
Cictm1c(KOMP)Wtsi/Cictm1c(KOMP)Wtsi
Neurod6tm1(cre)Kan/Neurod6+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N 		decreased cerebral cortex cell number J:240674
Cictm1c(KOMP)Wtsi/Cictm1c(KOMP)Wtsi
Tg(Otp-cre)1Hzo/0
involves: C57BL/6 * C57BL/6N * FVB/N 		abnormal response to social novelty J:240674
abnormal social investigation J:240674
increased aggression towards mice J:240674
normal nervous system phenotype J:240674
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory