Bbs10 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bbs10
Bardet-Biedl syndrome 10
MGI:1919019

26 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bbs10^{tm1.1(KOMP)Vlcg}/Bbs10⁺ B6N(Cg)-Bbs10^{tm1.1(KOMP)Vlcg}/J	increased circulating sodium level	J:211773
Bbs10^{tm1.1(KOMP)Vlcg}/Bbs10^{tm1.1(KOMP)Vlcg} B6N(Cg)-Bbs10^{tm1.1(KOMP)Vlcg}/J	preweaning lethality, complete penetrance	J:211773
Bbs10^tm1.1Vmar/Bbs10^tm1.1Vmar Tg(Cdh16-cre)91Igr/0 involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:227230
Bbs10^tm1.2Vmar/Bbs10^tm1.2Vmar involves: 129P2/OlaHsd * C57BL/6	abnormal glucose tolerance	J:227230
	abnormal photoreceptor outer segment morphology	J:227230
	abnormal renal tubule epithelium morphology	J:227230
	abnormal retina apoptosis	J:227230
	abnormal rod electrophysiology	J:227230
	absent podocyte foot process	J:227230
	normal adipose tissue phenotype	J:227230
	decreased body weight	J:227230
	decreased renal glomerulus basement membrane thickness	J:227230
	decreased total retina thickness	J:227230
	increased body weight	J:227230
	increased circulating antidiuretic hormone level	J:227230
	increased circulating leptin level	J:227230
	increased urine flow rate	J:227230
	increased urine microalbumin level	J:227230
	obese	J:227230
	photoreceptor inner segment degeneration	J:227230
	photoreceptor outer segment degeneration	J:227230
	polyphagia	J:227230
	polyuria	J:227230
	retina degeneration	J:227230
	retina outer nuclear layer degeneration	J:227230
	retina photoreceptor degeneration	J:227230

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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