Ap2b1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ap2b1
adaptor-related protein complex 2, beta 1 subunit
MGI:1919020

17 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ap2b1^b2b2321Clo/Ap2b1^b2b2321Clo C57BL/6J-Ap2b1^b2b2321Clo	abnormal aortic arch morphology	J:175213
	atrioventricular septal defect	J:175213
	cleft palate	J:175213
	double outlet right ventricle with atrioventricular septal defect	J:175213
	double outlet right ventricle, Taussig bing type	J:175213
	heart left ventricle hypertrophy	J:175213
	heart right ventricle hypertrophy	J:175213
	micrognathia	J:175213
	overriding aortic valve	J:175213
	perimembraneous ventricular septal defect	J:175213
	right aortic arch	J:175213
	thymus hypoplasia	J:175213
Ap2b1^em1(IMPC)J/Ap2b1⁺ C57BL/6NJ-Ap2b1^em1(IMPC)J/J	decreased grip strength	J:211773
Ap2b1^em1(IMPC)J/Ap2b1^em1(IMPC)J C57BL/6NJ-Ap2b1^em1(IMPC)J/J	abnormal embryo size	J:211773
	cleft palate	J:211773
	preweaning lethality, complete penetrance	J:211773
Ap2b1^mpc187H/Ap2b1^mpc187H involves: BALB/c * C3H/HeH * C57BL/6J	hyperactivity	J:234901
Ap2b1^{Tg(Tyr)427Ove}/Ap2b1^{Tg(Tyr)427Ove} FVB/NJ-Ap2b1^{Tg(Tyr)427Ove}	abnormal palatal shelf fusion at midline	J:177760
	cleft palate	J:177760

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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