Dync2i2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dync2i2
dynein 2 intermediate chain 2
MGI:1919070

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dync2i2^tm1Blnw/Dync2i2^tm1Blnw involves: 129S6/SvEvTac * C57BL/6 * Swiss Webster	abnormal apical ectodermal ridge morphology	J:242833
	abnormal embryonic neuroepithelium primary cilium morphology	J:242833
	abnormal limb bud morphology	J:242833
	abnormal limb mesenchyme morphology	J:242833
	abnormal limb paddle morphology	J:242833
	abnormal microtubule cytoskeleton morphology	J:242833
	abnormal neural tube morphology	J:242833
	abnormal primary cilium morphology	J:242833
	embryonic growth retardation	J:242833
	embryonic lethality during organogenesis, incomplete penetrance	J:242833
	exencephaly	J:242833
	lethality throughout fetal growth and development, complete penetrance	J:242833
	microphthalmia	J:242833
	open neural tube	J:242833
	polydactyly	J:242833
	spina bifida	J:242833
Dync2i2^{Tn(pb-Act-RFP)1.1Zhu}/Dync2i2^{Tn(pb-Act-RFP)1.1Zhu} involves: C57BL/6 * FVB/NJ	abnormal cilium morphology	J:335806
	abnormal heart looping	J:335806
	abnormal telencephalon morphology	J:335806
	decreased midbrain size	J:335806
	embryonic growth retardation	J:335806
	embryonic lethality during organogenesis, complete penetrance	J:335806
	open neural tube	J:335806

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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