Lancl2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lancl2
LanC (bacterial lantibiotic synthetase component C)-like 2
MGI:1919085

9 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lancl2^em1Vdd/Lancl2^em1Vdd FVB/N-Lancl2^em1Vdd	no abnormal phenotype detected	J:249809
Lancl2^{tm2a(KOMP)Wtsi}/Lancl2^{tm2a(KOMP)Wtsi} involves: C57BL/6N	decreased macrophage cell number	J:250673
	decreased regulatory T cell number	J:250673
	decreased susceptibility to bacterial infection	J:250673
Lancl2^{tm2b(KOMP)Wtsi}/Lancl2^{tm2b(KOMP)Wtsi} C57BL/6N-Lancl2^{tm2b(KOMP)Wtsi}/Ucd	abnormal coat/hair pigmentation	J:211773
	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	enlarged heart	J:211773
	enlarged kidney	J:211773
Lancl2^{tm2c(KOMP)Wtsi}/Lancl2^{tm2c(KOMP)Wtsi} Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: C57BL/6N	decreased macrophage cell number	J:250673
	decreased regulatory T cell number	J:250673
	decreased susceptibility to bacterial infection	J:250673

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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