Borcs6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Borcs6
BLOC-1 related complex subunit 6
MGI:1919173

26 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Borcs6^{tm1.1(KOMP)Vlcg}/Borcs6⁺ B6N(Cg)-Borcs6^{tm1.1(KOMP)Vlcg}/J	increased circulating calcium level	J:211773
	increased total body fat amount	J:211773
Borcs6^{tm1.1(KOMP)Vlcg}/Borcs6^{tm1.1(KOMP)Vlcg} B6N(Cg)-Borcs6^{tm1.1(KOMP)Vlcg}/J	abnormal cell nucleus morphology	J:329966
	abnormal developmental patterning	J:329966
	abnormal distal visceral endoderm morphology	J:329966
	abnormal egg cylinder morphology	J:279207
	abnormal embryo morphology	J:329966
	abnormal embryonic epiblast morphology	J:329966
	abnormal extraembryonic ectoderm morphology	J:329966
	abnormal lysosome morphology	J:329966
	abnormal primitive streak formation	J:329966
	abnormal vesicle-mediated transport	J:329966
	abnormal visceral endoderm morphology	J:329966
	absent head fold	J:279207
	absent primitive node	J:279207
	decreased embryo size	J:279207, J:329966
	decreased embryonic epiblast cell proliferation	J:329966
	embryonic growth arrest	J:279207
	embryonic lethality between implantation and placentation, complete penetrance	J:279207
	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to organogenesis, complete penetrance	J:329966
	failure of primitive streak formation	J:279207
	failure to gastrulate	J:279207
	increased embryonic tissue cell apoptosis	J:329966
	preweaning lethality, complete penetrance	J:211773
	small embryonic epiblast	J:329966

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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