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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Apol6
apolipoprotein L 6
MGI:1919189
34 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Apol6em1Hsul/Apol6em1Hsul
Not Specified 		abnormal fat cell differentiation J:344362
decreased body fat mass J:344362
decreased body weight J:344362
decreased circulating cholesterol level J:344362
decreased circulating HDL cholesterol level J:344362
decreased circulating triglyceride level J:344362
decreased epididymal fat pad weight J:344362
decreased inflammatory response J:344362
decreased renal fat pad weight J:344362
decreased susceptibility to diet-induced obesity J:344362
decreased white adipose tissue mass J:344362
decreased white fat cell size J:344362
enhanced lipolysis J:344362
improved glucose tolerance J:344362
increased circulating free fatty acids level J:344362
increased insulin sensitivity J:344362
Tg(Adipoq-Apol6)#Hsul/0
C57BL/6J-Tg(Adipoq-Apol6)#Hsul 		impaired glucose tolerance J:344362
impaired lipolysis J:344362
increased body weight J:344362
increased epididymal fat pad weight J:344362
increased renal fat pad weight J:344362
increased white adipose tissue mass J:344362
increased white fat cell size J:344362
insulin resistance J:344362
white adipose tissue inflammation J:344362
Tg(Fabp4-Apol6)#Hsul/0
C57BL/6J-Tg(Fabp4-Apol6)#Hsul 		abnormal circulating glycerol level J:344362
decreased circulating free fatty acids level J:344362
impaired glucose tolerance J:344362
impaired lipolysis J:344362
increased body fat mass J:344362
increased body weight J:344362
increased circulating cholesterol level J:344362
increased circulating HDL cholesterol level J:344362
increased circulating LDL cholesterol level J:344362
increased circulating triglyceride level J:344362
increased epididymal fat pad weight J:344362
increased liver triglyceride level J:344362
increased renal fat pad weight J:344362
increased susceptibility to diet-induced hepatic steatosis J:344362
increased white adipose tissue mass J:344362
increased white fat cell size J:344362
insulin resistance J:344362
white adipose tissue inflammation J:344362
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory