Ppp2r2a Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppp2r2a
protein phosphatase 2, regulatory subunit B, alpha
MGI:1919228

9 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppp2r2a^igt10/Ppp2r2a⁺ involves: C3H/HeH * C57BL/6J	increased circulating insulin level	J:246319
	increased pancreatic beta cell mass	J:246319
	insulin resistance	J:246319
Ppp2r2a^{tm1b(KOMP)Wtsi}/Ppp2r2a⁺ C57BL/6N-Ppp2r2a^{tm1b(KOMP)Wtsi}/Nju	abnormal bone structure	J:211773
	decreased body length	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased lean body mass	J:211773
Ppp2r2a^{tm1b(KOMP)Wtsi}/Ppp2r2a^{tm1b(KOMP)Wtsi} C57BL/6N-Ppp2r2a^{tm1b(KOMP)Wtsi}/Nju	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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