Esco2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
MGI:1919238

14 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Emx1^tm1(cre)Krj/Emx1⁺ Esco2^tm1.1Ge/Esco2^tm1.1Ge involves: 129S2/SvPas * C57BL/6 * SJL	abnormal embryonic neuroepithelium morphology	J:180371
	abnormal hippocampus development	J:180371
	abnormal neocortex morphology	J:180371
	abnormal neuronal precursor proliferation	J:180371
	absent hippocampus	J:180371
	increased neuron apoptosis	J:180371
	microcephaly	J:180371
Esco2^tm1.1Ge/Esco2^tm1.1Ge Ndor1^{Tg(UBC-cre/ERT2)1Ejb}/Ndor1⁺ involves: 129S2/SvPas * C57BL/6 * SJL	abnormal mitosis	J:296958
Esco2^tm1.1Ge/Esco2^tm1.1Ge Tg(CAG-cre/Esr1)5Amc/0 involves: 129S2/SvPas C57BL/6 * CBA * SJL	abnormal cell nucleus morphology	J:180371
	abnormal chromosome morphology	J:180371
	abnormal mitosis	J:180371
	decreased cell proliferation	J:180371
	increased mitotic index	J:180371
Esco2^tm1.2Ge/Esco2^tm1.2Ge involves: 129S2/SvPas * C57BL/6 * FVB/N * SJL	abnormal mitosis	J:180371
	abnormal preimplantation embryo development	J:180371
	embryonic lethality before implantation, complete penetrance	J:180371

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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