Pdxp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
MGI:1919282

25 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pdxp^em1(IMPC)J/Pdxp^em1(IMPC)J C57BL/6NJ-Pdxp^em1(IMPC)J/Mmjax	abnormal bone structure	J:211773
	decreased bone mineral content	J:211773
	hyperactivity	J:211773
	increased lean body mass	J:211773
	increased leukocyte cell number	J:211773
Pdxp^tm1.1Ango/Pdxp^tm1.1Ango Tg(ACTA1-cre)79Jme/0 involves: C57BL/6J * SJL	increased grip strength	J:270551
Pdxp^tm1.1Ango/Pdxp^tm1.1Ango Tg(Nes-cre)1Kln/0 involves: C57BL/6J * SJL	decreased grip strength	J:270551
Pdxp^tm1.2Ango/Pdxp^tm1.2Ango involves: C57BL/6J	abnormal amino acid level	J:270551
	abnormal emotion/affect behavior	J:270551
	abnormal spatial reference memory	J:270551
	abnormal vitamin level	J:270551
	decreased glutamine level	J:270551
	decreased glycine level	J:270551
	decreased grip strength	J:270551
	decreased methionine level	J:270551
	decreased phenylalanine level	J:270551
	enhanced spatial learning	J:270551
	increased alanine level	J:270551
	increased anxiety-related response	J:270551
	increased gamma-aminobutyric acid level	J:270551
	increased serine level	J:270551
	increased thigmotaxis	J:270551
	increased threonine level	J:270551
	normal mortality/aging	J:270551
	muscle weakness	J:270551
	normal reproductive system phenotype	J:270551

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24