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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dusp11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
MGI:1919352
13 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dusp11Gt(BB0198)Wtsi/Dusp11Gt(BB0198)Wtsi
B6.129P2-Dusp11Gt(BB0198)Wtsi 		abnormal macrophage activation involved in immune response J:301503
normal immune system phenotype J:301503
increased circulating interleukin-1 beta level J:301503
increased circulating interleukin-6 level J:301503
increased circulating tumor necrosis factor level J:301503
increased macrophage cytokine production J:301503
increased susceptibility to endotoxin shock J:301503
increased susceptibility to induced morbidity/mortality J:301503
Dusp11tm1b(EUCOMM)Wtsi/Dusp11tm1b(EUCOMM)Wtsi
C57BL/6N-Dusp11tm1b(EUCOMM)Wtsi/Ics 		abnormal cornea morphology J:211773
abnormal locomotor behavior J:211773
decreased total retina thickness J:211773
increased circulating aspartate transaminase level J:211773
prolonged QRS complex duration J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory