Dhx36 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dhx36
DEAH-box helicase 36
MGI:1919412

25 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dhx36^tm1.1Pmt/Dhx36^tm1.1Pmt involves: 129P2/Ola * C57BL/6	embryonic lethality between implantation and somite formation, complete penetrance	J:185179
Dhx36^tm1.2Pmt/Dhx36^tm1.2Pmt Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ involves: 129P2/Ola * 129S4/SvJaeSor * C57BL/6 * C57BL/10 * CBA/Ca	abnormal cell cycle	J:185179
	abnormal erythrocyte physiology	J:185179
	abnormal erythropoiesis	J:185179
	abnormal proerythroblast morphology	J:185179
	anemia	J:185179
	decreased erythroblast number	J:185179
	decreased erythrocyte cell number	J:185179
	decreased granulocyte monocyte progenitor cell number	J:185179
	decreased hemoglobin content	J:185179
	enlarged liver	J:185179
	enlarged spleen	J:185179
	hemolytic anemia	J:185179
	increased erythroblast number	J:185179
	increased hematopoietic stem cell number	J:185179
	increased mean corpuscular volume	J:185179
	increased megakaryocyte-erythroid progenitor cell number	J:185179
	intermingled spleen red and white pulp	J:185179
	pale kidney	J:185179
	pale liver	J:185179
	pallor	J:185179
	reticulocytosis	J:185179
	spherocytosis	J:185179
	thymus hypoplasia	J:185179
Dhx36^tm1.2Pmt/Dhx36^tm1.2Pmt Tg(Mx1-cre)1Cgn/0 involves: 129P2/Ola * 129S4/SvJaeSor * C57BL/6 * CBA	abnormal erythropoiesis	J:185179
	abnormal leukopoiesis	J:185179

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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