Klhl40 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Klhl40
kelch-like 40
MGI:1919580

16 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Klhl40^em1(IMPC)J/Klhl40^em1(IMPC)J C57BL/6NJ-Klhl40^em1(IMPC)J/Mmjax	preweaning lethality, incomplete penetrance	J:211773
Klhl40^{tm1(KOMP)Vlcg}/Klhl40^{tm1(KOMP)Vlcg} C57BL/6-Klhl40^{tm1(KOMP)Vlcg}	abnormal muscle physiology	J:213780
	abnormal sarcomere morphology	J:213780
	abnormal skeletal muscle morphology	J:213780
	abnormal Z line morphology	J:213780
	decreased body size	J:213780
	decreased heart rate	J:213780
	impaired skeletal muscle contractility	J:213780
	muscle weakness	J:213780
	myopathy	J:213780
	postnatal growth retardation	J:213780
	postnatal lethality, complete penetrance	J:213780
	small heart	J:213780
Klhl40^tm1.1Itl/Klhl40^tm1.1Itl involves: 129S6/SvEvTac * C57BL/6N	abnormal sarcomere morphology	J:227534
	decreased body size	J:227534
	decreased skeletal muscle fiber size	J:227534
	increased skeletal muscle cell apoptosis	J:227534
	postnatal lethality, complete penetrance	J:227534
	slow postnatal weight gain	J:227534

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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