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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Amer1
APC membrane recruitment 1
MGI:1919595
58 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Amer1tm1.1Nbar/Y
Tg(BGLAP-cre)1Clem/0
involves: 129S4/SvJae * C57BL/6 * FVB/NJ * SJL 		normal skeleton phenotype J:173242
Amer1tm1.1Nbar/Y
Tg(Col2a1-cre)1Bhr/0
involves: 129S4/SvJae * C57BL/6 * SJL 		normal skeleton phenotype J:173242
Amer1tm1.1Nbar/Y
Tg(Prrx1-cre)1Cjt/0
involves: 129S4/SvJae * C57BL/6 * SJL 		abnormal appendicular skeleton morphology J:173242
abnormal bone structure J:173242
abnormal compact bone morphology J:173242
abnormal deltoid tuberosity morphology J:173242
abnormal fat cell differentiation J:173242
abnormal fat cell morphology J:173242
abnormal long bone morphology J:173242
abnormal osteoblast differentiation J:173242
abnormal sternum morphology J:173242
abnormal sternum ossification J:173242
abnormal trabecular bone morphology J:173242
delayed bone mineralization J:173242
increased bone mineralization J:173242
increased bone ossification J:173242
increased bone volume J:173242
increased osteoblast cell number J:173242
increased trabecular bone thickness J:173242
osteosclerosis J:173242
Amer1tm1.1Nbar/Y
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL 		abnormal bone structure J:173242
abnormal skeleton development J:173242
delayed fontanelle closure J:173242
increased bone mineralization J:173242
increased bone ossification J:173242
increased bone volume J:173242
increased osteoblast cell number J:173242
increased trabecular bone thickness J:173242
large fontanelles J:173242
osteosclerosis J:173242
Amer1tm1.2Nbar/Y
involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL 		abnormal bone mineralization J:173242
abnormal compact bone morphology J:173242
abnormal cranial suture morphology J:173242
abnormal deltoid tuberosity morphology J:173242
abnormal endochondral bone ossification J:173242
abnormal intramembranous bone ossification J:173242
abnormal kidney development J:173242
abnormal kidney morphology J:173242
abnormal long bone morphology J:173242
abnormal metanephric mesenchyme morphology J:173242
abnormal neurocranium morphology J:173242
abnormal skeleton morphology J:173242
abnormal sternum morphology J:173242
abnormal sternum ossification J:173242
abnormal ulna morphology J:173242
abnormal ureteric bud morphology J:173242
abnormal Wolffian duct morphology J:173242
absent deltoid tuberosity J:173242
absent kidney J:173242
bowed radius J:173242
bowed ulna J:173242
cyanosis J:173242
decreased brown adipose tissue amount J:173242
decreased total body fat amount J:173242
decreased white adipose tissue amount J:173242
delayed endochondral bone ossification J:173242
delayed intramembranous bone ossification J:173242
enlarged cranium J:173242
enlarged heart J:173242
enlarged kidney J:173242
enlarged neurocranium J:173242
increased cranium width J:173242
increased fetal size J:173242
increased fetal weight J:173242
increased heart weight J:173242
increased metanephric mesenchyme apoptosis J:173242
increased radius size J:173242
neonatal lethality, complete penetrance J:173242
osteosclerosis J:173242
single kidney J:173242
spleen hypoplasia J:173242
Amer1tm1.2Nbar/Amer1+
involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL 		increased bone mineral density J:173242
increased fetal size J:173242
increased fetal weight J:173242
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory