Ripk4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ripk4
receptor-interacting serine-threonine kinase 4
MGI:1919638

34 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ripk4^{tm1a(EUCOMM)Wtsi}/Ripk4⁺ C57BL/6N-Ripk4^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased body weight	J:175295
Ripk4^tm1Pmh/Ripk4^tm1Pmh involves: 129	normal craniofacial phenotype	J:184926
Ripk4^tm1Pmh/Ripk4^tm1Pmh involves: 129 * C57BL/6	abnormal actin cytoskeleton morphology	J:259661
	abnormal epidermis suprabasal layer morphology	J:78593
	abnormal forelimb morphology	J:259661
	abnormal genital tubercle morphology	J:259661
	abnormal hindlimb morphology	J:78593, J:259661
	abnormal keratinocyte differentiation	J:78593, J:259661
	abnormal nose morphology	J:78593
	abnormal periderm development	J:259661
	abnormal periderm morphology	J:259661
	abnormal secondary palate development	J:259661
	abnormal skin appearance	J:78593
	abnormal tail morphology	J:78593
	abnormal vibrissa morphology	J:78593
	absent epidermis stratum corneum	J:78593
	absent vibrissae	J:78593
	anal atresia	J:78593
	cleft palate	J:259661
	epidermal hyperplasia	J:78593
	esophageal atresia	J:78593, J:259661
	failure of palatal shelf elevation	J:259661
	normal hematopoietic system phenotype	J:78593
	normal immune system phenotype	J:78593
	impaired skin barrier function	J:259661
	interdigital webbing	J:78593
	oral atresia	J:78593, J:259661
	palatal shelf fusion with tongue or mandible	J:259661
	parakeratosis	J:78593
	perinatal lethality, complete penetrance	J:78593
	short hindlimb	J:78593
	short tail	J:78593
	thick epidermis	J:78593
	thick skin	J:78593

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24