Rspo3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rspo3
R-spondin 3
MGI:1920030

22 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rspo3^tm1.1Arte/Rspo3^tm1.1Arte either: (involves: C57BL/6) or (involves: C57BL/6 * CD-1)	abnormal angiogenesis	J:215739
	abnormal placenta morphology	J:215739
	abnormal vitelline vasculature morphology	J:215739
	embryonic growth arrest	J:215739
	hemorrhage	J:215739
	pale yolk sac	J:215739
Rspo3^tm1.1Jcob/Rspo3^tm1.1Jcob involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL	no abnormal phenotype detected	J:188812
Rspo3^tm1.1Jcob/Rspo3^tm1.2Jcob Tg(Prrx1-cre)1Cjt/0 involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL	short limbs	J:188812
Rspo3^tm1.2Jcob/Rspo3^tm1.2Jcob involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL	decreased embryo size	J:188812
	embryonic growth arrest	J:188812
	embryonic lethality during organogenesis, complete penetrance	J:188812
	enlarged pericardium	J:188812
	hemorrhage	J:188812
	pale yolk sac	J:188812
Rspo3^tm1Arte/Rspo3^tm1Arte Isl1^tm1(cre)Sev/Isl1⁺ involves: 129 * C57BL/6	abnormal cardiac outflow tract development	J:214093
	abnormal heart right ventricle morphology	J:214093
	blood vessel congestion	J:214093
	embryonic lethality during organogenesis, complete penetrance	J:214093
	pericardial edema	J:214093
	thin myocardium	J:214093
Rspo3^tm1Arte/Rspo3^tm1Arte Isl1^tm1(cre)Tmj/Isl1⁺ involves: 129X1/SvJ * C57BL/6	decreased heart right ventricle size	J:214093
	double outlet right ventricle	J:214093
	lethality throughout fetal growth and development, complete penetrance	J:214093
	pericardial edema	J:214093
Rspo3^tm1Okam/Rspo3^tm1Okam involves: 129P2/OlaHsd	abnormal placenta labyrinth morphology	J:116978
	abnormal placental labyrinth vasculature morphology	J:116978
	decreased embryo size	J:116978
	embryonic growth arrest	J:116978
	prenatal lethality, complete penetrance	J:116978

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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