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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pot1b
protection of telomeres 1B
MGI:1920086
26 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pot1bTgTn(sb-cHS4,Tyr)2325D-8c1aOve/Pot1bTgTn(sb-cHS4,Tyr)2325D-8c1aOve
FVB/N-Pot1bTgTn(sb-cHS4,Tyr)2325D-8c1aOve 		abnormal pluripotent precursor cell morphology J:175597
neonatal lethality, complete penetrance J:175597
Pot1btm1.1Schg/Pot1btm1.1Schg
Terctm1Rdp/Terc+
involves: 129/Sv * 129S6/SvEvTac * C57BL/6 * SJL 		abnormal blood cell morphology/development J:144553
abnormal crypts of Lieberkuhn morphology J:144553
abnormal definitive hematopoiesis J:144553
abnormal granulocyte morphology J:144553
abnormal nail morphology J:144553
abnormal spermatogenesis J:144553
absent bone marrow cell J:144553
anemia J:144553
decreased body weight J:144553
decreased erythrocyte cell number J:144553
decreased granulocyte number J:144553
decreased hematopoietic stem cell number J:144553
decreased leukocyte cell number J:144553
decreased male germ cell number J:144553
hyperpigmentation J:144553
impaired hematopoiesis J:144553
increased apoptosis J:144553
premature death J:144553
small testis J:144553
thrombocytopenia J:144553
Pot1btm1.1Schg/Pot1btm1.1Schg
Terctm1Rdp/Terctm1Rdp
involves: 129/Sv * 129S6/SvEvTac * C57BL/6 * SJL 		abnormal erythrocyte morphology J:144553
abnormal granulocyte morphology J:144553
abnormal intestine morphology J:144553
abnormal spermatogenesis J:144553
absent bone marrow cell J:144553
decreased male germ cell number J:144553
pancytopenia J:144553
postnatal lethality, complete penetrance J:144553
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory