Setd5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Setd5
SET domain containing 5
MGI:1920145

101 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Setd5^tm1.1Mgn/Setd5^tm1.1Mgn involves: 129S6/SvEvTac * CD-1	abnormal heart morphology	J:237500
	abnormal myocardial trabeculae morphology	J:237500
	abnormal myocardium layer morphology	J:237500
	abnormal placenta labyrinth morphology	J:237500
	abnormal placenta morphology	J:237500
	abnormal placental labyrinth vasculature morphology	J:237500
	abnormal somite development	J:237500
	abnormal tail bud morphology	J:237500
	abnormal vascular development	J:237500
	abnormal vascular plexus formation	J:237500
	abnormal vitelline vasculature morphology	J:237500
	decreased embryo size	J:237500
	disorganized yolk sac vascular plexus	J:237500
	embryonic growth retardation	J:237500
	embryonic lethality during organogenesis, complete penetrance	J:237500
	enlarged heart	J:237500
	normal hematopoietic system phenotype	J:237500
	hemorrhage	J:237500
	increased embryonic tissue cell apoptosis	J:237500
	pericardial effusion	J:237500
Setd5^{tm1a(EUCOMM)Wtsi}/Setd5⁺ C57BL/6N-Setd5^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal aortic valve cusp morphology	J:239583
	abnormal auditory brainstem response	J:211773
	abnormal cervical rib	J:239583
	abnormal coat/hair pigmentation	J:211773
	abnormal coronary sinus morphology	J:239583
	abnormal cranium morphology	J:211773
	abnormal ductus venosus topology	J:239583
	abnormal ductus venosus valve topology	J:239583
	abnormal eye muscle morphology	J:239583
	abnormal forebrain morphology	J:239583
	abnormal hepatic portal vein connection	J:239583
	abnormal hindbrain morphology	J:239583
	abnormal hypoglossal nerve topology	J:239583
	abnormal incisor morphology	J:211773
	abnormal maxilla morphology	J:211773
	abnormal olfactory bulb morphology	J:239583
	abnormal optic cup morphology	J:239583
	abnormal optic stalk morphology	J:239583
	abnormal pineal gland morphology	J:239583
	abnormal snout morphology	J:211773
	abnormal superior vena cava morphology	J:239583
	abnormal thymus morphology	J:239583
	abnormal tooth morphology	J:211773
	abnormal vertebral artery topology	J:239583
	abnormal vitelline vein connection	J:239583
	abnormal vitelline vein topology	J:239583
	absent brachiocephalic trunk	J:239583
	absent ductus venosus valve	J:239583
	absent pectinate muscle	J:239583
	absent pinna reflex	J:211773
	absent segment of posterior cerebral artery	J:239583
	anastomosis between internal carotid artery and basilar artery	J:239583
	atrial septal defect	J:239583
	bicuspid aortic valve	J:239583
	blood in lymph vessels	J:239583
	decreased circulating glucose level	J:211773
	decreased grip strength	J:211773
	dilated hepatic portal vein	J:239583
	dilated liver sinusoidal space	J:239583
	double inlet heart left ventricle	J:239583
	double outlet right ventricle	J:239583
	dual inferior vena cava	J:239583
	ductus venosus stenosis	J:239583
	enlarged lymphatic vessel	J:239583
	enlarged orbital veins	J:239583
	enlarged paraumbilical vein	J:239583
	fetal growth retardation	J:239583
	fusion of vertebral arches	J:239583
	increased monocyte cell number	J:211773
	increased regulatory T cell number	J:211773
	intraembryonal intestine elongation	J:239583
	muscular ventricular septal defect	J:239583
	perimembraneous ventricular septal defect	J:239583
	persistent right dorsal aorta	J:239583
	persistent truncus arteriosus	J:239583
	reduced sympathetic cervical ganglion size	J:239583
	right aortic arch	J:239583
	small kidney	J:239583
	small superior cervical ganglion	J:239583
	small thymus	J:239583
	small thyroid gland	J:239583
	subcutaneous edema	J:239583
	symmetric azygos veins	J:239583
	vertebral fusion	J:211773
Setd5^{tm1a(EUCOMM)Wtsi}/Setd5^{tm1a(EUCOMM)Wtsi} C57BL/6N-Setd5^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal chorion morphology	J:261316
	abnormal placenta morphology	J:261316
	abnormal trophoblast layer morphology	J:261316
	abnormal visceral yolk sac morphology	J:261316
	lethality throughout fetal growth and development, complete penetrance	J:261316
	preweaning lethality, complete penetrance	J:211773
Setd5^{tm1c(EUCOMM)Wtsi}/Setd5⁺ Tmem163^{Tg(ACTB-cre)2Mrt}/Tmem163⁺ involves: C57BL/6N * FVB/N	abnormal cardiac outflow tract development	J:314464
	double outlet right ventricle	J:314464
	overriding aortic valve	J:314464
	perimembraneous ventricular septal defect	J:314464
Setd5^{tm1c(EUCOMM)Wtsi}/Setd5⁺ Mesp1^tm2(cre)Ysa/Mesp1⁺ involves: C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj	dilated heart ventricle	J:314464
Setd5^{tm1c(EUCOMM)Wtsi}/Setd5^{tm1c(EUCOMM)Wtsi} Mesp1^tm2(cre)Ysa/Mesp1⁺ involves: C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj	abnormal cardiac outflow tract development	J:314464
	abnormal heart atrium morphology	J:314464
	abnormal heart morphology	J:314464
	abnormal heart shape	J:314464
	abnormal interventricular groove morphology	J:314464
	common atrium	J:314464
	common ventricle	J:314464
	decreased embryo size	J:314464
	dilated heart	J:314464
	dilated heart atrium	J:314464
	dilated heart ventricle	J:314464
	embryonic lethality during organogenesis, complete penetrance	J:314464
	heart right ventricle hypoplasia	J:314464
	hemorrhage	J:314464
	pericardial effusion	J:314464
Setd5^{tm1c(EUCOMM)Wtsi}/Setd5^{tm1c(EUCOMM)Wtsi} Tbx1^tm6(cre)Bld/Tbx1⁺ involves: C57BL/6N	normal cardiovascular system phenotype	J:314464

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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