Insig2 Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Insig2
insulin induced gene 2
MGI:1920249

11 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Insig1^tm1.1Mbjg/Insig1^tm1.1Mbjg Insig2^tm1Mbjg/Insig2⁺ involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N	postnatal lethality	J:101203
Insig1^tm1.1Mbjg/Insig1^tm1.1Mbjg Insig2^tm1Mbjg/Insig2^tm1Mbjg involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N	postnatal lethality	J:101203
Insig1^tm1Mbjg/Insig1^tm1Mbjg Insig2^tm1Mbjg/Insig2^tm1Mbjg Tg(Mx1-cre)29-4Her/0 involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl * SJL	abnormal cholesterol homeostasis	J:101203
	abnormal hepatobiliary system physiology	J:101203
	abnormal lipid homeostasis	J:101203
	abnormal liver morphology	J:101203
	decreased circulating triglyceride level	J:101203
	increased circulating cholesterol level	J:101203
	increased fatty acids level	J:101203
	increased liver cholesterol level	J:101203
	increased liver triglyceride level	J:101203
	pale liver	J:101203

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24