Trmt10a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trmt10a
tRNA methyltransferase 10A
MGI:1920421

22 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Trmt10a^em1Tomik/Trmt10a^em1Tomik C57BL/6N-Trmt10a^em1Tomik	abnormal postsynaptic density morphology	J:358937
	abnormal spatial reference memory	J:358937
	decreased body weight	J:358937
	decreased brain weight	J:358937
	normal endocrine/exocrine gland phenotype	J:358937
	normal homeostasis/metabolism phenotype	J:358937
	impaired coordination	J:358937
	impaired spatial learning	J:358937
	impaired synaptic plasticity	J:358937
	normal liver/biliary system phenotype	J:358937
	normal renal/urinary system phenotype	J:358937
Trmt10a^{tm1a(EUCOMM)Wtsi}/Trmt10a^{tm1a(EUCOMM)Wtsi} C57BL/6N-Trmt10a^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal lens morphology	J:175295
	cataract	J:175295
	decreased body weight	J:175295
	decreased circulating alanine transaminase level	J:175295
	decreased circulating aspartate transaminase level	J:175295
	decreased circulating cholesterol level	J:175295
	decreased circulating HDL cholesterol level	J:175295
	decreased circulating LDL cholesterol level	J:175295
	increased circulating free fatty acids level	J:175295
	increased circulating glycerol level	J:175295
	increased sacral vertebrae number	J:175295
Trmt10a^{tm1a(EUCOMM)Wtsi}/Trmt10a^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	increased circulating magnesium level	J:200082

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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