Ttc21b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ttc21b
tetratricopeptide repeat domain 21B
MGI:1920918

20 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ttc21b^aln/Ttc21b^aln B6.A(FVB)-Ttc21b^aln	absent olfactory bulb	J:282171
	forebrain hypoplasia	J:282171
	microcephaly	J:282171
Ttc21b^aln/Ttc21b^aln involves: A/J	abnormal brain morphology	J:75360
	abnormal craniofacial morphology	J:75360
	abnormal limb bone morphology	J:75360
	abnormal neural tube morphology	J:75360
	abnormal vertebrae morphology	J:75360
	absent olfactory bulb	J:75360
	polycystic kidney	J:213263
	polydactyly	J:75360
	rib fusion	J:75360
	truncated ribs	J:75360
Ttc21b^aln/Ttc21b^aln involves: A/J * FVB	absent olfactory bulb	J:282171
	forebrain hypoplasia	J:282171
	microcephaly	J:282171
Ttc21b^m1Btlr/Ttc21b^m1Btlr C57BL/6J-Ttc21b^m1Btlr	increased body weight	J:265171
Ttc21b^{tm2c(KOMP)Wtsi}/Ttc21b^aln Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺ involves: 129S1/Sv * 129X1/SvJ * A/J * C57BL/6N	abnormal kidney morphology	J:213263
	abnormal loop of Henle morphology	J:213263
	decreased kidney epithelial cell primary cilium length	J:213263
	dilated proximal convoluted tubule	J:213263
	increased blood urea nitrogen level	J:213263
	increased kidney cell proliferation	J:213263
	increased kidney weight	J:213263
	polycystic kidney	J:213263

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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