Cst6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cst6
cystatin E/M
MGI:1920970

34 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cst6^{em1(IMPC)Ccpcz}/Cst6⁺ C57BL/6NCrl-Cst6^{em1(IMPC)Ccpcz}/Ccpcz	abnormal digit morphology	J:211773
	abnormal heart morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal rib morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal uterus morphology	J:211773
	decreased circulating serum albumin level	J:211773
	enlarged heart	J:211773
	enlarged spleen	J:211773
	hydrometra	J:211773
	increased circulating creatine kinase level	J:211773
	long tibia	J:211773
	rib fusion	J:211773
	small spleen	J:211773
Cst6^{em1(IMPC)Ccpcz}/Cst6^{em1(IMPC)Ccpcz} C57BL/6NCrl-Cst6^{em1(IMPC)Ccpcz}/Ccpcz	no spontaneous movement	J:211773
	preweaning lethality, complete penetrance	J:211773
Cst6^ichq/Cst6⁺ involves: BALB/cJ	abnormal hair follicle morphology	J:41426
	abnormal mitochondrial morphology	J:41426
	abnormal sebaceous gland morphology	J:41426
	abnormal skin condition	J:41426
	abnormal skin morphology	J:41426
	decreased body size	J:41426
	decreased body weight	J:90417
	epidermal hyperplasia	J:41426
	hyperkeratosis	J:41426
	increased keratinocyte proliferation	J:41426
	mixed cellular infiltration to dermis	J:41426
	orthokeratosis	J:79976
	postnatal lethality, complete penetrance	J:41426, J:79976, J:90417
	scaly skin	J:41426
	small sebaceous gland	J:41426
	sparse hair	J:41426
	thick epidermis	J:41426
	thick skin	J:41426

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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