Cby1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cby1
chibby family member 1, beta catenin antagonist
MGI:1920989

34 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cby1^tm1Ktkm/Cby1^tm1Ktkm B6.129-Cby1^tm1Ktkm	abnormal club cell morphology	J:166685
	abnormal lung hysteresivity	J:166685
	abnormal pulmonary alveolar parenchyma morphology	J:166685
	abnormal pulmonary alveolar sac morphology	J:166685
	abnormal pulmonary alveolus epithelial cell morphology	J:166685
	abnormal respiratory conducting tube morphology	J:166685
	abnormal respiratory epithelium morphology	J:147413, J:166685
	abnormal respiratory mechanics	J:166685
	abnormal respiratory motile cilium morphology	J:166685
	abnormal type I pneumocyte morphology	J:166685
	abnormal type II pneumocyte morphology	J:166685
	anemia	J:147413
	decreased airway resistance	J:166685
	decreased body size	J:147413
	decreased hematocrit	J:147413
	decreased lung compliance	J:166685
	decreased respiratory motile cilia number	J:147413, J:166685
	decreased subcutaneous adipose tissue amount	J:147413
	decreased survivor rate	J:147413
	normal embryo phenotype	J:147413
	impaired lung alveolus development	J:166685
	impaired mucociliary clearance	J:147413
	increased alveolar lamellar body number	J:166685
	increased lung elastance	J:166685
	increased lung tissue damping	J:166685
	increased susceptibility to bacterial infection	J:147413
	increased susceptibility to otitis media	J:147413
	male infertility	J:147413
	overexpanded pulmonary alveolus	J:166685
	postnatal lethality, incomplete penetrance	J:147413
	pulmonary hypoplasia	J:166685
	sinus inflammation	J:147413
	slow postnatal weight gain	J:166685
Cby1^tm1Ktkm/Cby1^tm1Ktkm Not Specified	abnormal fat cell differentiation	J:122334

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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