Thap1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Thap1
THAP domain containing, apoptosis associated protein 1
MGI:1921004

14 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Thap1^em1(IMPC)J/Thap1⁺ C57BL/6NJ-Thap1^em1(IMPC)J/Mmjax	abnormal cornea morphology	J:211773
Thap1^em1(IMPC)J/Thap1⁺ C57BL/6NJ-Thap1^em1(IMPC)J/Mmjax	increased grip strength	J:211773
Thap1^em1(IMPC)J/Thap1^em1(IMPC)J C57BL/6NJ-Thap1^em1(IMPC)J/Mmjax	embryonic growth retardation	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Thap1^tm1.1Meeh/Thap1⁺ involves: 129S/SvEv * C3H * C57BL/6	abnormal cerebellum dentate nucleus morphology	J:226849
	abnormal gait	J:226849
	decreased brain size	J:226849
Thap1^tm1.1Meeh/Thap1^tm1.1Meeh involves: 129S/SvEv * C3H * C57BL/6	embryonic lethality, complete penetrance	J:226849
Thap1^tm1.1Meeh/Thap1^tm1.2Meeh involves: 129S/SvEv * BALB/cJ * C3H * C57BL/6	abnormal axon extension	J:226849
	absent liver	J:226849
	anophthalmia	J:226849
	decreased brain size	J:226849
	enlarged brain ventricles	J:226849
	lethality throughout fetal growth and development, complete penetrance	J:226849
Thap1^tm1.2Meeh/Thap1⁺ involves: 129S/SvEv * BALB/cJ * C3H * C57BL/6	abnormal cerebellum dentate nucleus morphology	J:226849
	abnormal gait	J:226849
	decreased brain size	J:226849
Thap1^tm1.2Meeh/Thap1^tm1.2Meeh involves: 129S/SvEv * BALB/cJ * C3H * C57BL/6	abnormal axon extension	J:226849
	absent liver	J:226849
	anophthalmia	J:226849
	decreased brain size	J:226849
	enlarged brain ventricles	J:226849
	lethality throughout fetal growth and development, complete penetrance	J:226849

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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