Nphp3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nphp3
nephronophthisis 3 (adolescent)
MGI:1921275

35 phenotypes from 4 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nphp3^em1(IMPC)J/Nphp3⁺ C57BL/6NJ-Nphp3^em1(IMPC)J/Mmjax	increased grip strength	J:211773
Nphp3^em1(IMPC)J/Nphp3^em1(IMPC)J C57BL/6NJ-Nphp3^em1(IMPC)J/Mmjax	preweaning lethality, incomplete penetrance	J:211773
Nphp3^pcy/Nphp3^pcy D2.KK-Nphp3^pcy	enlarged kidney	J:129264
Nphp3^pcy/Nphp3^pcy D2.KK-Nphp3^pcy	polycystic kidney	J:129264
Nphp3^pcy/Nphp3^pcy either: D2.KK-Nphp3^pcy or (involves: DBA/2Fg * DBA/2J * KK)	abnormal renal glomerular capsule morphology	J:11399
	abnormal renal tubule morphology	J:11399
	dilated distal convoluted tubule	J:11399
	dilated kidney collecting duct	J:11399
	dilated renal glomerular capsule	J:11399
	enlarged kidney	J:11399
	increased blood urea nitrogen level	J:11399
	increased kidney weight	J:11399
	intracranial aneurysm	J:11399
	kidney cyst	J:11399
	kidney inflammation	J:11399
	malocclusion	J:11399
	premature death	J:11399
	premature tooth eruption	J:11399
	renal interstitial fibrosis	J:11399
Nphp3^pcy/Nphp3^pcy involves: DBA/2Fg * KK	abnormal cholesterol homeostasis	J:2203
	abnormal circulating phospholipid level	J:2203
	abnormal phospholipid level	J:2203
	enlarged kidney	J:2203
	increased circulating cholesterol level	J:2203
	kidney cyst	J:2203
Nphp3^pcy/Nphp3^pcy involves: KK	kidney cyst	J:91453
Nphp3^pcy/Nphp3^pcy involves: KK	polycystic kidney	J:244067
Nphp3^pcy/Nphp3^pcy KK-Nphp3^pcy	anemia	J:8302
	distended abdomen	J:8302
	enlarged kidney	J:8302
	increased blood urea nitrogen level	J:8302
	increased kidney weight	J:8302
	kidney cyst	J:8302
	kidney inflammation	J:8302
	lethargy	J:8302
	premature death	J:8302
	tremors	J:8302
Nphp3^pcy/Nphp3^tm1Cbe involves: C57BL/6 * CD-1 * KK/Upj	abnormal renal tubule epithelial cell primary cilium morphology	J:139258
	dilated renal tubule	J:139258
	kidney cyst	J:139258
Nphp3^pol/Nphp3^pol C57BL/6JSfdAnu-Nphp3^pol/Anu	enlarged kidney	J:104190
	exencephaly	J:104190
	increased blood urea nitrogen level	J:104190
	kidney inflammation	J:104190
	polycystic kidney	J:104190
	postnatal lethality	J:104190
	renal fibrosis	J:104190
Nphp3^tm1Cbe/Nphp3^tm1Cbe B6.129P2-Nphp3^tm1Cbe	abnormal embryo turning	J:139258
	abnormal heart morphology	J:139258
	abnormal left-right axis patterning	J:139258
	prenatal lethality, complete penetrance	J:139258

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