About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Vsir
V-set immunoregulatory receptor
MGI:1921298
12 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Cd274tm1Igu/Cd274tm1Igu
Vsirtm1Lex/Vsirtm1Lex
involves: 129S5/SvEvBrd * C57BL/6 		abnormal T cell activation J:222944
Pdcd1tm1Hon/Pdcd1tm1Hon
Vsirtm1Lex/Vsirtm1Lex
involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6 		abnormal T cell activation J:222944
hepatic necrosis J:222944
normal immune system phenotype J:222944
increased IgA level J:222944
increased IgM level J:222944
increased inflammatory response J:222944
increased interferon-gamma secretion J:222944
increased interleukin-17 secretion J:222944
increased tumor necrosis factor secretion J:222944
pancreas necrosis J:222944
pulmonary necrosis J:222944
Pdcd1tm1Hon/Pdcd1tm1Hon
Vsirtm1Lex/Vsirtm1Lex
Tg(Tcra2D2,Tcrb2D2)1Kuch/0
involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6 		increased susceptibility to experimental autoimmune encephalomyelitis J:222944
Vsirtm1Lex/Vsirtm1Lex
Tg(Tcra2D2,Tcrb2D2)1Kuch/0
involves: 129S5/SvEvBrd * C57BL/6 		increased susceptibility to experimental autoimmune encephalomyelitis J:222944
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory