Syce1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Syce1
synaptonemal complex central element protein 1
MGI:1921325

27 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Syce1^em1Rrca/Syce1^em1Rrca involves: C57BL/6J	abnormal chromosomal synapsis	J:309952
	abnormal ovary morphology	J:309952
	abnormal spermatogenesis	J:309952
	absent oocytes	J:309952
	absent ovarian follicles	J:309952
	arrest of male meiosis	J:309952
	azoospermia	J:309952
	infertility	J:309952
	small ovary	J:309952
	small seminiferous tubules	J:309952
	small testis	J:309952
Syce1^{tm1b(KOMP)Wtsi}/Syce1^{tm1b(KOMP)Wtsi} C57BL/6N-Syce1^{tm1b(KOMP)Wtsi}/J	abnormal lens morphology	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased grip strength	J:211773
	decreased locomotor activity	J:211773
	female infertility	J:211773
	improved glucose tolerance	J:211773
	increased fasting circulating glucose level	J:211773
	increased thigmotaxis	J:211773
	increased urine microalbumin level	J:211773
	limb grasping	J:211773
	male infertility	J:211773
Syce1^tm1Hgu/Syce1^tm1Hgu involves: 129S7/SvEvBrd * C57BL/6	abnormal double-strand DNA break repair	J:146770
	abnormal synaptonemal complex	J:146770
	arrest of male meiosis	J:146770
	azoospermia	J:146770
	decreased mature ovarian follicle number	J:146770
	female infertility	J:146770
	increased male germ cell apoptosis	J:146770
	male infertility	J:146770
	small ovary	J:146770
	small testis	J:146770

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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