Cep55 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cep55
centrosomal protein 55
MGI:1921357

46 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cep55^em1(IMPC)Tcp/Cep55⁺ C57BL/6NCrl-Cep55^em1(IMPC)Tcp/Tcp	abnormal ovary morphology	J:211773
	abnormal sternum morphology	J:211773
	small kidney	J:211773
	small uterus	J:211773
Cep55^em1(IMPC)Tcp/Cep55^em1(IMPC)Tcp C57BL/6NCrl-Cep55^em1(IMPC)Tcp/Tcp	preweaning lethality, complete penetrance	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Cep55^em1.1Hyli/Cep55^em1.1Hyli involves: C57BL/6	abnormal brain ventricle morphology	J:313163
	abnormal cell cycle	J:313163
	abnormal choroid plexus morphology	J:313163
	abnormal dorsal striatum morphology	J:313163
	abnormal embryonic neuroepithelium primary cilium morphology	J:313163
	abnormal hippocampus morphology	J:313163
	abnormal primary cilium morphology	J:313163
	abnormal thalamus morphology	J:313163
	normal craniofacial phenotype	J:313163
	decreased cell proliferation	J:313163
	dilated lateral ventricle	J:313163
	dilated third ventricle	J:313163
	enlarged brain ventricles	J:313163
	hydrocephaly	J:313163
	increased brain ependyma motile cilium length	J:313163
	increased kidney epithelial cell primary cilium length	J:313163
	kidney cyst	J:313163
	normal limbs/digits/tail phenotype	J:313163
	postnatal lethality, complete penetrance	J:313163
	renal glomerulus cyst	J:313163
	small cerebellum	J:313163
	thin cerebral cortex	J:313163
Cep55^{tm1a(EUCOMM)Hmgu}/Cep55^{tm1a(EUCOMM)Hmgu} involves: C57BL/6N	abnormal cerebral cortex morphology	J:287102
	abnormal cranium morphology	J:287102
	abnormal kidney cortex morphology	J:287102
	abnormal mitotic cytokinesis	J:287102
	abnormal motor capabilities/coordination/movement	J:287102
	abnormal renal glomerulus morphology	J:287102
	absent gastric milk in neonates	J:287102
	decreased body weight	J:287102
	decreased brain size	J:287102
	decreased brain weight	J:287102
	decreased cerebral cortex cell density	J:287102
	decreased neuronal precursor cell number	J:287102
	increased cell nucleus count	J:287102
	increased neuron apoptosis	J:287102
	microcephaly	J:287102
	pallor	J:287102
	postnatal lethality, incomplete penetrance	J:287102
	thin cerebral cortex	J:287102
Cep55^{tm1c(EUCOMM)Hmgu}/Cep55^{tm1c(EUCOMM)Hmgu} Gt(ROSA)26Sor^{tm9(cre/ESR1)Arte}/Gt(ROSA)26Sor⁺ involves: C57BL/6N * C57BL/6NTac	increased cell nucleus count	J:287102
Cep55^{tm1c(EUCOMM)Hmgu}/Cep55^{tm1c(EUCOMM)Hmgu} Tg(Vil1-cre)20Syr/0 involves: C57BL/6N * DBA/2	normal digestive/alimentary phenotype	J:287102

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24