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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lonp1
lon peptidase 1, mitochondrial
MGI:1921392
12 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Lonp1tm1b(EUCOMM)Hmgu/Lonp1+
C57BL/6N-Lonp1tm1b(EUCOMM)Hmgu/Ieg 		abnormal lens morphology J:211773
decreased circulating iron level J:211773
decreased prepulse inhibition J:211773
increased circulating HDL cholesterol level J:211773
Lonp1tm1b(EUCOMM)Hmgu/Lonp1tm1b(EUCOMM)Hmgu
C57BL/6N-Lonp1tm1b(EUCOMM)Hmgu/Ieg 		preweaning lethality, complete penetrance J:211773
Lonp1tm1Otin/Lonp1+
Not Specified 		decreased incidence of tumors by chemical induction J:221992
Lonp1tm1Otin/Lonp1tm1Otin
Not Specified 		abnormal inner cell mass morphology J:221992
abnormal trophoblast giant cell morphology J:221992
decreased embryo size J:221992
decreased mitochondrial DNA content J:221992
embryonic growth retardation J:221992
embryonic lethality between implantation and placentation, incomplete penetrance J:221992
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory