Acot12 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Acot12
acyl-CoA thioesterase 12
MGI:1921406

13 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Acot12^{em1(IMPC)Hmgu}/Acot12^{em1(IMPC)Hmgu} C57BL/6NCrl-Acot12^{em1(IMPC)Hmgu}/Ieg	abnormal vocalization	J:211773
	decreased cardiac muscle contractility	J:211773
	dilated heart left ventricle	J:211773
Acot12^em1Holi/Acot12^em1Holi involves: C57BL/6J * C57BL/6N	abnormal ion homeostasis	J:335836
	abnormal phospholipid level	J:335836
	increased circulating cholesterol level	J:335836
	increased circulating phospholipid level	J:335836
	increased hepatocellular carcinoma incidence	J:335836
	increased incidence of tumors by chemical induction	J:335836
	increased liver cholesterol level	J:335836
	increased liver triglyceride level	J:335836
	increased tumor growth/size	J:335836
	liver fibrosis	J:335836

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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