Gbe1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gbe1
1,4-alpha-glucan branching enzyme 1
MGI:1921435

37 phenotypes from 5 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gbe1^m1Yty/Gbe1^m1Yty C3HeB/FeJ-Gbe1^m1Yty	abnormal fetal cardiomyocyte proliferation	J:167233
	abnormal heart ventricle morphology	J:167233
	blood vessel congestion	J:167233
	decreased cardiac muscle glycogen level	J:167233
	decreased heart left ventricle size	J:167233
	decreased heart rate	J:167233
	edema	J:167233
	lethality throughout fetal growth and development, complete penetrance	J:167233
	liver vascular congestion	J:167233
	pulmonary vascular congestion	J:167233
	thin myocardium	J:167233
	ventricular septal defect	J:167233
Gbe1^tm1.1Hoa/Gbe1^tm1.1Hoa involves: 129S7/SvEvBrd	abnormal glucose homeostasis	J:176889
	abnormal heart morphology	J:176889
	abnormal muscle physiology	J:176889
	decreased liver glycogen level	J:176889
	decreased skeletal muscle glycogen level	J:176889
	perinatal lethality, complete penetrance	J:176889
Gbe1^tm1Hoa/Gbe1^tm1Hoa involves: 129S7/SvEvBrd	abnormal brain morphology	J:176889
	abnormal glucose tolerance	J:176889
	abnormal heart morphology	J:176889
	abnormal liver morphology	J:176889
	abnormal skeletal muscle morphology	J:176889
	decreased circulating glucose level	J:176889
	decreased glycogen catabolism rate	J:176889
	increased liver glycogen level	J:176889
	increased skeletal muscle glycogen level	J:176889
	premature death	J:176889
Gbe1^tm2.1Hoa/Gbe1^tm2.1Hoa involves: 129S7/SvEvBrd	abnormal glucose homeostasis	J:226481
	abnormal muscle glycogen level	J:226481
	decreased fasting circulating glucose level	J:226481
	decreased grip strength	J:226481
	hindlimb paralysis	J:226481
	increased brain glycogen level	J:226481
	increased circulating creatine kinase level	J:226481
	increased glycogen level	J:226481
	increased liver glycogen level	J:226481
	liver fibrosis	J:226481
	premature death	J:226481
	spasticity	J:226481
	weakness	J:226481
Gbe1^tm2Hoa/Gbe1^tm2Hoa involves: 129S7/SvEvBrd	abnormal muscle glycogen level	J:226481
	increased brain glycogen level	J:226481
	increased glycogen level	J:226481
	increased liver glycogen level	J:226481
	premature death	J:226481

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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